Archive List for Organic Chemistry

Aromatic Heterocyclic Compounds: Reactivity and Orientation

Organic Chemistry

There are many types of compounds that have aromatic properties. All compounds are aromatic if they have a benzene ring in the molecule. However, there are aromatic compounds that are different from benzene rings. These are heterocyclic compounds. Aromatic heterocyclic compounds show aromaticity but have different properties from benzene rings. What should we pay attention […]

Diels-Alder Reaction of Pericyclic Reactions: Dienes and Dienophiles

Organic Chemistry

When synthesizing a compound with a six-membered ring, there is one synthetic reaction to consider first; the pericyclic reaction. Among the pericyclic reactions, the most famous is the Diels-Alder reaction. In organic chemical reactions, Lewis acids and Lewis bases are usually involved in the reaction. In the pericyclic reaction, however, acids and bases are not […]

Claisen Condensation and Dieckmann Condensation: Decarboxylation, Choice of Base

Organic Chemistry

One way to create a new carbon chain is through synthetic reactions using enolates. One of the organic chemical syntheses with enolates is Claisen condensation. In Claisen condensation, molecules with esters react with enolates. As a result, new carbonyl compounds can be obtained. When Claisen condensation occurs intramolecularly, it is called Dieckmann condensation (intramolecular Claisen […]

Carbonyl Reduction: Hydride Reduction with NaBH4 and LiAlH4

Organic Chemistry

It is important in organic chemistry to change the form of the functional group to get the substituent you want. When you perform a synthetic reaction, you have to synthesize a compound that has the functional group you want. One of those synthetic reactions is carbonyl reduction. Among the reduction reactions, the reduction of carbonyl […]

HSAB Theory: Meaning the Hard/Soft of Acids and Bases

Organic Chemistry

In organic chemistry, synthetic reactions are often carried out by acids and bases. The reaction of a Lewis acid and a Lewis base creates new bonds. So when a compound reacts chemically, what kind of atoms bond with each other? In this regard, the HSAB theory (or HSAB principle) helps us to predict where compounds […]

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