Archive List for Organic Chemistry

Carbonyl Reduction: Hydride Reduction of NaBH4 and LiAlH4

Organic Chemistry

Changing the form of the functional group to the substituent you want is important in organic chemistry. When you perform a synthetic reaction, you have to synthesize a compound that has the functional group you want. One of those synthetic reactions is carbonyl reduction. Among the reduction reactions, the reduction of carbonyl compounds is an […]

HSAB Theory: Meaning the Hard/Soft of Acids and Bases

Organic Chemistry

In organic chemistry, synthetic reactions are often carried out by acids and bases. The reaction of a Lewis acid and a Lewis base creates new bonds. So when a compound reacts chemically, which types of atoms bond with each other? In this regard, the HSAB theory (or HSAB principle) helps us to predict where compounds […]

Nucleophilic Acyl Substitution with Carboxylic Acid Derivatives

Organic Chemistry

Compounds with a C=O structure are carbonyl compounds, and there are many types of carbonyl compounds. Among these carbonyl compounds, carbonyl compounds that can be synthesized from carboxylic acids are called carboxylic acid derivatives. There are different types of carboxylic acid derivatives, such as acyl chloride, acid anhydride, esters and amides. Since their reactivity and […]

Nucleophilic Aromatic Substitution: Sandmeyer Reaction and Benzyne

Organic Chemistry

The synthesis of aromatic compounds is very important because organic compounds with benzene rings are common. Compounds with aromatic rings are highly stable and usually do not react chemically. In some cases, however, it is possible to replace substituents on the aromatic rings. This is called nucleophilic aromatic substitution. If a leaving group is present […]

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